Histiocytosis
Clinical Research
The main objective of the Histiocytosis Research Program is to improve the understanding and treatment of Langerhans cell histiocytosis and Hemagophagocytic Lymphohistiocytosis. Program faculty actively contribute to and participate in internally led research initiatives as well as those directed by the Histiocyte Society, an international research collaboration.
Following are some of the research initiatives under way in the research program:
- The program treats patients in accordance with protocols established by the Histiocyte Society. LCH patients are offered the opportunity to take part in LCH III. HLH patients may participate in the HLH 2004 study.
- A clinical database has been established to identify patterns of disease in patients with LCH and to determine the effectiveness of their treatments.
- In collaboration with the laboratory of Barrett Rollins, MD, PhD, of Dana-Farber, the program is evaluating the biology of histiocytic disorders. The families of patients undergoing biopsies of histiocytic lesions are offered the chance to participate in a study that uses pathologic material that would otherwise be discarded.
